4-Methyl-5-(4-methyl-piperazine-1-sulfonyl)-thiazol-2-ylamine → 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [4-methyl-5-(4-methyl-piperazine-1-sulfonyl)-thiazol-2-yl]-amide
Reaction equation
[CH3:27][c:28]1[n:29][c:30]([NH2:43])[s:31][c:32]1[S:33](=[O:34])(=[O:35])[N:36]1[CH2:37][CH2:38][N:39]([CH3:42])[CH2:40][CH2:41]1.[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[OH:14])([F:25])[F:26]>>[F:1][C:2]([c:3]1[cH:4][c:5](-[c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12](=[O:13])[NH:43][c:30]1[n:29][c:28]([CH3:27])[c:32]([S:33](=[O:34])(=[O:35])[N:36]2[CH2:37][CH2:38][N:39]([CH3:42])[CH2:40][CH2:41]2)[s:31]1)([F:25])[F:26]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-35ce0bad7ce44c78b798be7055101668
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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