Bicarbonate Ion → O1-benzyl O2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate

HRID 822732Notes

Reaction equation

HRID 822732 reaction equation
[C:23](=[O:24])([OH:25])[O-:26].[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:11](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:7][CH:8]([OH:10])[CH2:9]1.[Cl:28][CH2:29][Cl:30].[F-:21].[Na+:22].[Na+:27]>>[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:11](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:7][CH:8]([F:21])[CH2:9]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 28179Fluoride IonHCID 3253131-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 11666328O1-benzyl O2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-4424b517a4ba4f2490c0f334b2655149
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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