1-Butanol → N-[2-(2-Hydroxyethoxy)-ethyl]-4,4-diphenylpiperidine

HRID 822958Notes

Reaction equation

HRID 822958 reaction equation
[C:19](=[O:20])([O-:21])[O-:22].[CH2:33]([OH:34])[CH2:35][CH2:36][CH3:37].[I-:26].[K+:23].[K+:24].[K+:25].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:8][CH2:9][N:10]([CH2:31][CH2:32][O:27][CH2:28][CH2:29][OH:30])[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 2631-ButanolHCID 813Potassium Cation3×HCID 19660Carbonate IonHCID 30165Iodide IonHCID 312751,4-DioxaneHCID 28232394,4-Diphenylpiperidine

Product 1

HCID 19988807N-[2-(2-Hydroxyethoxy)-ethyl]-4,4-diphenylpiperidine

Sources & evidence

ORD record
ord-bb6a73a902ed44f3b779dc39709dbcee
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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