4-Benzylpiperidine → 4-Benzyl-1-({5-[4-(trifluoromethyl)phenyl]isoxazol-4-yl}carbonyl)piperidine
Reaction equation
[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[CH:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:14](=[O:15])[OH:16])[cH:11][n:12][o:13]2)[cH:7][cH:8]1)([F:17])[F:18]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:14](=[O:16])[N:29]3[CH2:28][CH2:27][CH:26]([CH2:19][c:20]4[cH:21][cH:22][cH:23][cH:24][cH:25]4)[CH2:31][CH2:30]3)[cH:11][n:12][o:13]2)[cH:7][cH:8]1)([F:17])[F:18]Participants
3
Sources & evidence
- ORD record
- ord-6e33d2aa7e674ba5b87baf694afe1206
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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