3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 7-(3-Chloro-4-fluorophenyl)-5-ethyl-5-thien-3-yl-1,5-dihydro-4,1-benzoxazepin-2(3H)-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[C:7]([c:13]1[cH:14][s:15][cH:16][cH:17]1)([CH2:18][CH3:19])[O:8][CH2:9][C:10](=[O:12])[NH:11]2.[Cl:21][c:22]1[cH:23][c:24]([B:29]([OH:30])[OH:31])[cH:25][cH:26][c:27]1[F:28]>>[c:2]1(-[c:24]2[cH:23][c:22]([Cl:21])[c:27]([F:28])[cH:26][cH:25]2)[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[C:7]([c:13]1[cH:14][s:15][cH:16][cH:17]1)([CH2:18][CH3:19])[O:8][CH2:9][C:10](=[O:12])[NH:11]2Participants
3
Sources & evidence
- ORD record
- ord-fd909ce29fe646f3af2782fde69c489f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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