HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclopropyl-3-oxopropanenitrile → 3-Cyclopropyl-1'-methyl-1'H-[1,4']bipyrazolyl-5-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclopropyl-3-oxopropanenitrile | HCID 9812763 | — |
| Reactant | di-tert-butyl 1-(1-methyl-1H-pyrazol-4-yl)hydrazine-1,2-dicarboxylate | HCID 11426954 | — |
| Product | 3-Cyclopropyl-1'-methyl-1'H-[1,4']bipyrazolyl-5-ylamine | HCID 70817252 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 296: using di-tert-butyl 1-(1-methyl-1H-pyrazol-4-yl)hydrazine-1,2-dicarboxylate (Preparation 295) and 3-cyclopropyl-3-oxopropanenitrile to afford the title compound in 48% yield, 1.7 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846698B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-11eebda06cdc4a778d8bf1ce3bfc14a1 |
| Source note | uspto-grants-2014_09 |