Dichloromethane → [4-(1-Ethylcarbamoyl-piperidin-4-yloxy)-6-fluoro-naphthalen-2-yl]-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7]2[cH:8][cH:9][c:10]([F:22])[cH:11][c:12]2[c:13]([O:15][CH:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:14]1)=[O:23].[Cl:29][CH2:30][Cl:31].[N:24](=[C:25]=[O:26])[CH2:27][CH3:28]>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7]2[cH:8][cH:9][c:10]([F:22])[cH:11][c:12]2[c:13]([O:15][CH:16]2[CH2:17][CH2:18][N:19]([C:25]([NH:24][CH2:27][CH3:28])=[O:26])[CH2:20][CH2:21]2)[cH:14]1)=[O:23]Participants
4
Sources & evidence
- ORD record
- ord-bdcf7c770f7f48f8be2f4ef811cf383e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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