Ethyl 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-carboxylate → 2-(4-Chlorophenyl)-5-({3-[2-methyl-4-(pyrrolidin-1-ylmethyl)phenoxy]azetidin-1-yl}carbonyl)-1,3,4-oxadiazole

HRID 823246Notes

Reaction equation

HRID 823246 reaction equation
[Cl:19][c:20]1[cH:21][cH:22][c:23](-[c:26]2[n:27][n:28][c:29]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[o:30]2)[cH:24][cH:25]1.[NH:1]1[CH2:2][CH:3]([O:5][c:6]2[c:7]([CH3:18])[cH:8][c:9]([CH2:10][N:11]3[CH2:12][CH2:13][CH2:14][CH2:15]3)[cH:16][cH:17]2)[CH2:4]1>>[N:1]1([C:31]([c:29]2[n:28][n:27][c:26](-[c:23]3[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]3)[o:30]2)=[O:32])[CH2:2][CH:3]([O:5][c:6]2[c:7]([CH3:18])[cH:8][c:9]([CH2:10][N:11]3[CH2:12][CH2:13][CH2:14][CH2:15]3)[cH:16][cH:17]2)[CH2:4]1

Participants

3

Reactant 2

HCID 46742983Ethyl 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-carboxylateHCID 666561701-(4-(Azetidin-3-yloxy)-3-methylbenzyl)pyrrolidine

Product 1

HCID 565978502-(4-Chlorophenyl)-5-({3-[2-methyl-4-(pyrrolidin-1-ylmethyl)phenoxy]azetidin-1-yl}carbonyl)-1,3,4-oxadiazole

Sources & evidence

ORD record
ord-4cf7c3bada9240699f26b7d7cb531f52
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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