Acetic Acid → 5-[4-(5-Fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylidenamino]-2-methylquinoline

HRID 823301Notes

Reaction equation

HRID 823301 reaction equation
[CH3:36][C:37](=[O:38])[OH:39].[CH3:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[F:1][c:2]1[cH:3][c:4]([C:11]([CH2:12][C:13]([CH:14]=[O:15])([C:16]([F:17])([F:18])[F:19])[OH:20])([CH3:21])[CH3:22])[c:5]2[c:6]([cH:10]1)[CH2:7][CH2:8][O:9]2.[NH2:23][c:24]1[c:25]2[cH:26][cH:27][c:28]([CH3:34])[n:29][c:30]2[cH:31][cH:32][cH:33]1.[OH2:35]>>[F:1][c:2]1[cH:3][c:4]([C:11]([CH2:12][C:13]([CH:14]=[N:23][c:24]2[c:25]3[cH:26][cH:27][c:28]([CH3:34])[n:29][c:30]3[cH:31][cH:32][cH:33]2)([C:16]([F:17])([F:18])[F:19])[OH:20])([CH3:21])[CH3:22])[c:5]2[c:6]([cH:10]1)[CH2:7][CH2:8][O:9]2

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 962WaterHCID 1140TolueneHCID 1486835-Quinolinamine, 2-methyl-HCID 441849894-(2,3-Dihydro-5-fluoro-7-benzofuranyl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentanal

Product 1

HCID 441850445-[4-(5-Fluoro-2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-2-trifluoromethyl-pentylidenamino]-2-methylquinoline

Sources & evidence

ORD record
ord-7fbb749feecd4161a0962934862d42f5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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