1-Aminopyrrole → 5-fluoro-N4-(4-isopropoxyphenyl)-N2-(1H-pyrrol-1-yl)-2,4-pyrimidinediamine

HRID 823328Notes

Reaction equation

HRID 823328 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH:16]([CH3:17])[CH3:18])[cH:13][cH:14]2)[n:7]1.[NH2:20][n:21]1[cH:22][cH:23][cH:24][cH:25]1>>[c:2]1([NH:20][n:21]2[cH:22][cH:23][cH:24][cH:25]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH:16]([CH3:17])[CH3:18])[cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 1365891-AminopyrroleHCID 220607632-chloro-5-fluoro-N-(4-isopropoxyphenyl)-4-pyrimidineamine

Product 1

HCID 220603235-fluoro-N4-(4-isopropoxyphenyl)-N2-(1H-pyrrol-1-yl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-5306347ae4ff4a59a4d33be3d0e5884f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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