9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → 9-{4-[4-(5-fluoro-1-methyl-1H-benzimidazol-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide
Reaction equation
[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][Br:24])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26].[F:27][c:28]1[cH:29][c:30]2[c:31]([n:32]([CH3:41])[c:33]([N:35]3[CH2:36][CH2:37][NH:38][CH2:39][CH2:40]3)[n:34]2)[cH:42][cH:43]1>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:38]2[CH2:37][CH2:36][N:35]([c:33]3[n:32]([CH3:41])[c:31]4[c:30]([cH:29][c:28]([F:27])[cH:43][cH:42]4)[n:34]3)[CH2:40][CH2:39]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d9a1492b344f4fe2b91a1d4a8271ed85
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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