3-Chloro-4-(3-fluorobenzyloxy)aniline → Ethyl 4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

HRID 823399Notes

Reaction equation

HRID 823399 reaction equation
[Cl:19][c:20]1[cH:21][c:22]([NH2:23])[cH:24][cH:25][c:26]1[O:27][CH2:28][c:29]1[cH:30][c:31]([F:35])[cH:32][cH:33][cH:34]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1>>[c:2]1([NH:23][c:22]2[cH:21][c:20]([Cl:19])[c:26]([O:27][CH2:28][c:29]3[cH:30][c:31]([F:35])[cH:32][cH:33][cH:34]3)[cH:25][cH:24]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[s:8][c:9]1[c:10]2[CH2:11][N:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:13]1

Participants

3

Reactant 2

HCID 70592633-Chloro-4-(3-fluorobenzyloxy)anilineHCID 58116864Ethyl12-chloro-7-thia-4,9,11-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9,11-tetraene-4-carboxylate

Product 1

HCID 58116877Ethyl 4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate

Sources & evidence

ORD record
ord-1082dc3fc4e746bda19b90d49b20771c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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