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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 823532Generated: October 27, 2026

Dimethylformamide → N-(2-tert-butoxycarbonylamino-5-trifluoromethyl-phenyl)-malonamic acid benzyl ester

https://huagongshe.com/reaction/823532

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
ReactantBenzyl malonateHCID 22247814—
Reactanttert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamateHCID 24689211—
ProductN-(2-tert-butoxycarbonylamino-5-trifluoromethyl-phenyl)-malonamic acid benzyl esterHCID 68617235—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8bd97f2ba5ca484eabbd8d73d705702e
Source noteTest data from https://doi.org/10.1039/C8SC04228D