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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824035Generated: October 26, 2026

Water → 6-Amino-N-(5-(4-fluoro-phenoxy)-thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/824035

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantHexafluorophosphateHCID 9886—
Reactant6-Aminonicotinic acidHCID 18496—
ReactantBenzotriazol-1-yl-tris(dimethylamino)phosphaniumHCID 10938827—
ReactantC-(5-(4-fluorophenoxy)thiophen-2-yl)methylamineHCID 23130478—
Product6-Amino-N-(5-(4-fluoro-phenoxy)-thiophen-2-ylmethyl)-nicotinamideHCID 23130556—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e0b5e1965bed46c094d219a53a23fcd3
Source noteTest data from https://doi.org/10.1039/C8SC04228D