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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824068Generated: October 26, 2026

N-methyl-2-pyrrolidone → 8-((6-amino-4-chloro-2-pyridinyl)amino)-6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)imidazo[1,2-b]pyridazine-3-carboxamide

https://huagongshe.com/reaction/824068

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant1,4-DiaminocyclohexaneHCID 18374—
Reactant8-(6-amino-4-chloropyridin-2-ylamino)-6-chloro-N-(3-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624351—
Product8-((6-amino-4-chloro-2-pyridinyl)amino)-6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-917fdd6a32f4409aaa992f6fc478957c
Source noteTest data from https://doi.org/10.1039/C8SC04228D