Methanol → 3-[6-(4-benzoylpiperazin-1-yl)-4-methyl-1H-benzimidazol-2-yl]-4-[(1-hydroxy-3-phenylpropan-2-yl)amino]-1H-pyridin-2-one
Reaction equation
[C:35]([c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)(=[O:42])[Cl:43].[CH3:44][OH:45].[OH:1][CH2:2][CH:3]([CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[NH:11][c:12]1[c:13](-[c:19]2[n:20][c:21]3[c:22]([nH:23]2)[cH:24][c:25]([N:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:26][c:27]3[CH3:28])[c:14](=[O:18])[nH:15][cH:16][cH:17]1>>[OH:1][CH2:2][CH:3]([CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[NH:11][c:12]1[c:13](-[c:19]2[n:20][c:21]3[c:22]([nH:23]2)[cH:24][c:25]([N:29]2[CH2:30][CH2:31][N:32]([C:35]([c:36]4[cH:37][cH:38][cH:39][cH:40][cH:41]4)=[O:42])[CH2:33][CH2:34]2)[cH:26][c:27]3[CH3:28])[c:14](=[O:18])[nH:15][cH:16][cH:17]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-53c48de086e242cf8716db148fd549b5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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