Methanol → 5-Amino-4-[3-(2-aminosulfonylethyl)benzoyl]-1-(4-fluorophenyl)pyrazole

HRID 824170Notes

Reaction equation

HRID 824170 reaction equation
[CH3:28][OH:29].[NH2:1][c:2]1[c:3]([C:14]([c:15]2[cH:16][c:17]([CH:21]=[CH:22][S:23](=[O:24])(=[O:25])[NH2:26])[cH:18][cH:19][cH:20]2)=[O:27])[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1.[OH-:30].[OH-:32].[Pd+2:31]>>[NH2:1][c:2]1[c:3]([C:14]([c:15]2[cH:16][c:17]([CH2:21][CH2:22][S:23](=[O:24])(=[O:25])[NH2:26])[cH:18][cH:19][cH:20]2)=[O:27])[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 544874125-Amino-4-[3-(2-aminosulfonylethenyl)benzoyl]-1-(4-fluorophenyl)pyrazole

Product 1

HCID 99083165-Amino-4-[3-(2-aminosulfonylethyl)benzoyl]-1-(4-fluorophenyl)pyrazole

Sources & evidence

ORD record
ord-94fb72e448e043f9b57704748de07cbe
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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