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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824177Generated: October 25, 2026

Hydrochloric Acid → methyl 5-amino-4-[7-[[4-[(4-fluoropiperidin-1-yl)methyl]phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

https://huagongshe.com/reaction/824177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-FluoropiperidineHCID 2759159—
Reactantmethyl 5-amino-4-[7-[[4-(chloromethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoateHCID 67334081—
Productmethyl 5-amino-4-[7-[[4-[(4-fluoropiperidin-1-yl)methyl]phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoateHCID 67333925—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-65cb6952c3404629bdb51f253b64aec4
Source noteTest data from https://doi.org/10.1039/C8SC04228D