tert-Butanol → 6-[4-[2-[3-(2,5-dichlorophenoxy)-2-hydroxypropylamino]-2-methylpropylamino]phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone
Reaction equation
[C:34]([OH:35])([CH3:36])([CH3:37])[CH3:38].[Cl:21][c:22]1[c:23]([O:24][CH2:25][CH:26]2[CH2:27][O:28]2)[cH:29][c:30]([Cl:33])[cH:31][cH:32]1.[NH2:1][C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH:12]2[CH3:18])[cH:9][cH:10]1)([CH3:19])[CH3:20]>>[NH:1]([C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH:12]2[CH3:18])[cH:9][cH:10]1)([CH3:19])[CH3:20])[CH2:27][CH:26]([CH2:25][O:24][c:23]1[c:22]([Cl:21])[cH:32][cH:31][c:30]([Cl:33])[cH:29]1)[OH:28]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d512b8a5010d46888561842a608e143f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…