Methanol → 5-Fluoro-2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Reaction equation
[CH3:26][OH:27].[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[CH2:20][CH2:21][N:22]([CH3:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[cH:4][c:5]([O:11][CH3:12])[c:6]([N+:8]([O-:9])=[O:10])[cH:7]1>>[F:1][c:2]1[c:3]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[CH2:20][CH2:21][N:22]([CH3:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[cH:4][c:5]([O:11][CH3:12])[c:6]([NH2:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-1f93757b45444b409822c3ee59c3ca26
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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