Potassium Cation → tert-Butyl 4-ethynylpiperidine-1-carboxylate

HRID 824526Notes

Reaction equation

HRID 824526 reaction equation
[C:16](=[O:17])([O-:18])[O-:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]=[O:15])[CH2:12][CH2:13]1.[CH3:22][O:23][P:24]([C:25](=[N+:26]=[N-:27])[C:28](=[O:29])[CH3:30])(=[O:31])[O:32][CH3:33].[CH3:34][OH:35].[K+:20].[K+:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]#[CH:16])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylateHCID 136023029(1E)-1-diazo-1-dimethoxyphosphorylpropan-2-one

Product 1

HCID 15550481tert-Butyl 4-ethynylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-768483e7c20244e790b3218ad15210df
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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