4-Fluorobenzyl bromide → 2-(3,5-Dichlorophenyl)-4-[(4-fluorobenzyl)oxy]-6-isopropylpyrimidine
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]([CH:16]([CH3:17])[CH3:18])[cH:12][c:13]([OH:15])[n:14]2)[cH:5][c:6]([Cl:8])[cH:7]1.[F:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][Br:25])[cH:26][cH:27]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]([CH:16]([CH3:17])[CH3:18])[cH:12][c:13]([O:15][CH2:24][c:23]3[cH:22][cH:21][c:20]([F:19])[cH:27][cH:26]3)[n:14]2)[cH:5][c:6]([Cl:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-3b891dbc24114b8eb1d56b8459290238
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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