Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824707Generated: October 30, 2026

Diisopropylamine → Methyl 2-[4-[3-[4-[3-(4-hydroxypiperidin-1-yl)prop-1-ynyl]phenyl]-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetate

https://huagongshe.com/reaction/824707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-(Prop-2-yn-1-yl)piperidin-4-olHCID 18616723—
ReactantMethyl 2-[4-[3-(4-iodophenyl)-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetateHCID 90997013—
ProductMethyl 2-[4-[3-[4-[3-(4-hydroxypiperidin-1-yl)prop-1-ynyl]phenyl]-3-[3-(trifluoromethyl)phenyl]prop-2-enoxy]-2-methylphenoxy]acetateHCID 90945705—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4287f56510a64ee1a3be606633068301
Source noteTest data from https://doi.org/10.1039/C8SC04228D