3-Cyclopentyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]prop-2-enenitrile → 3 Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2.3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile

HRID 824762Notes

Reaction equation

HRID 824762 reaction equation
[CH:1]1([C:6](=[CH:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]4)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[H:32][H:33]>>[CH:1]1([CH:6]([CH2:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]4)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 665974453-Cyclopentyl-3-[4-[7-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]prop-2-enenitrileHCID 178418361HCID 178418361, compound

Product 1

HCID 574775973 Cyclopentyl-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2.3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile

Sources & evidence

ORD record
ord-4f269955492d48e7882b4fe85bd3c8f6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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