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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 824840Generated: October 30, 2026

Dichloromethane → 4-[3-(2-Cyclopropyl-pyridin-3-yl)-phenyl]-7-methyl-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/824840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant(2-{3-[3-(2-Cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 86589385—
Product4-[3-(2-Cyclopropyl-pyridin-3-yl)-phenyl]-7-methyl-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 22317130—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5cfb6a65576a4fe6b5e2d9123d881211
Source noteTest data from https://doi.org/10.1039/C8SC04228D