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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82491Generated: October 25, 2026

Trifluoroacetic acid → Amino-acetic acid 4-allyl-2-methoxy-phenyl ester Trifluoroacetate

https://huagongshe.com/reaction/82491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantAmino-acetic acid 4-allyl-2-methoxy-phenyl esterHCID 69920127—
SolventDichloromethaneHCID 6344—
ProductAmino-acetic acid 4-allyl-2-methoxy-phenyl ester TrifluoroacetateHCID 86674925—

Reaction Conditions

Temperature25 °C

Reaction Steps

To a solution of compound amino-acetic acid 4-allyl-2-methoxy-phenyl ester (0.3 g) in DCM (10 mL) was added trifluoroacetic acid (0.5 mL) drop wise at (0° C.). The mixture was allowed to stir at room temperature (25° C.) over a period of 2 h. Solvent was stripped off completely and the reaction was carried for the next step (510 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846721B2
Source datasetuspto-grants-2014_09
ORD IDord-94416477fee4402b9dae8b9b83cdb00f
Source noteuspto-grants-2014_09