Methanol → N-[(4-fluorophenyl)methyl]-3-hydroxy-5-methyl-4-oxo-7-(3-pyridyl)-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxamide

HRID 824985Notes

Reaction equation

HRID 824985 reaction equation
[CH3:32][OH:33].[F:23][c:24]1[cH:25][cH:26][c:27]([CH2:28][NH2:29])[cH:30][cH:31]1.[OH:1][c:2]1[c:3]([C:19](=[O:20])[O:21][CH3:22])[n:4][n:5]2[c:6]1[C:7](=[O:18])[N:8]([CH3:17])[CH2:9][CH:10]2[c:11]1[cH:12][n:13][cH:14][cH:15][cH:16]1>>[OH:1][c:2]1[c:3]([C:19](=[O:20])[NH:29][CH2:28][c:27]2[cH:26][cH:25][c:24]([F:23])[cH:31][cH:30]2)[n:4][n:5]2[c:6]1[C:7](=[O:18])[N:8]([CH3:17])[CH2:9][CH:10]2[c:11]1[cH:12][n:13][cH:14][cH:15][cH:16]1

Participants

4

Reactant 3

HCID 887MethanolHCID 673264-FluorobenzylamineHCID 68953024Methyl 3-hydroxy-5-methyl-4-oxo-7-pyridin-3-yl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate

Product 1

HCID 54678885N-[(4-fluorophenyl)methyl]-3-hydroxy-5-methyl-4-oxo-7-(3-pyridyl)-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxamide

Sources & evidence

ORD record
ord-828d61f27dd54f62ab4edfbef94a2ea2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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