Phenethyl tosylate → N-Benzyl-3-methyl-5-(2-oxo-4-phenethoxypyridin-1(2H)-yl)thiophene-2-carboxamide

HRID 825032Notes

Reaction equation

HRID 825032 reaction equation
[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[NH:27][C:28](=[O:29])[c:30]1[s:31][c:32](-[n:36]2[c:37](=[O:43])[cH:38][c:39]([OH:42])[cH:40][cH:41]2)[cH:33][c:34]1[CH3:35].[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6](=[O:7])(=[O:8])[O:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:9][cH:10]1>>[O:11]([CH2:12][CH2:13][c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[c:39]1[cH:38][c:37](=[O:43])[n:36](-[c:32]2[s:31][c:30]([C:28]([NH:27][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)=[O:29])[c:34]([CH3:35])[cH:33]2)[cH:41][cH:40]1

Participants

3

Reactant 2

HCID 20522Phenethyl tosylateHCID 54742340N-benzyl-5-(4-hydroxy-2-oxopyridin-1(2H)-yl)-3-methylthiophene-2-carboxamide

Product 1

HCID 24983970N-Benzyl-3-methyl-5-(2-oxo-4-phenethoxypyridin-1(2H)-yl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-39adf9ef65dd41e5870076f7e9d9da2f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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