8-(2,6-Dichloro-3,5-dimethoxy-phenyl)-quinoxaline-5-carboxylic acid [5-(4-methyl-piperazin-1-ylmethyl)-pyridin-2-yl]-amide → 8-(2-Fluoro-3,5-dimethoxy-phenyl)-quinoxaline-5-carboxylic acid [5-(4-methyl-piperazin-1-ylmethyl)-pyridin-2-yl]-amide
Reaction equation
[CH2:1]([O:3][C:4](=[O:2])[c:6]1[c:7]2[n:8][cH:9][cH:10][n:11][c:12]2[c:13](-[c:16]2[c:17]([F:26])[c:18]([O:24][CH3:25])[cH:19][c:20]([O:22][CH3:23])[cH:21]2)[cH:14][cH:15]1)[CH3:5].[CH3:27][N:28]1[CH2:29][CH2:30][N:31]([CH2:34][c:35]2[cH:36][cH:37][c:38]([NH:41][C:42]([c:43]3[c:44]4[n:45][cH:46][cH:47][n:48][c:49]4[c:50](-[c:51]4[c:52]([Cl:53])[c:54]([O:55][CH3:56])[cH:57][c:58]([O:59][CH3:60])[c:61]4[Cl:62])[cH:63][cH:64]3)=[O:65])[n:39][cH:40]2)[CH2:32][CH2:33]1>>[O:3]=[C:4]([c:6]1[c:7]2[n:8][cH:9][cH:10][n:11][c:12]2[c:13](-[c:16]2[c:17]([F:26])[c:18]([O:24][CH3:25])[cH:19][c:20]([O:22][CH3:23])[cH:21]2)[cH:14][cH:15]1)[NH:41][c:38]1[cH:37][cH:36][c:35]([CH2:34][N:31]2[CH2:30][CH2:29][N:28]([CH3:27])[CH2:33][CH2:32]2)[cH:40][n:39]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f14a374cb61c4237bc180299a87d4fd4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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