3-(4-Tert-butyl-phenyl)-4-cyano-5-trifluoromethyl-thiophene-2-carboxylic acid methyl ester → 4-Cyano-3-(2'-methylsulfanyl-biphenyl-4-yl)-5-trifluoromethyl-thiophene-2-carboxylic acid ethyl ester
Reaction equation
[CH2:26]([CH3:27])[O:28][C:29](=[O:30])[c:31]1[s:32][c:33]([I:52])[c:34]([C:50]#[N:51])[c:35]1-[c:36]1[cH:37][cH:38][c:39](-[c:42]2[c:43]([S:48][CH3:49])[cH:44][cH:45][cH:46][cH:47]2)[cH:40][cH:41]1.[CH3:1][O:2][C:3]([c:4]1[s:5][c:6]([C:22]([F:23])([F:24])[F:25])[c:7]([C:8]#[N:9])[c:10]1-[c:11]1[cH:12][cH:13][c:14]([C:15]([CH3:16])([CH3:17])[CH3:18])[cH:19][cH:20]1)=[O:21]>>[C:22]([F:23])([F:24])([F:25])[c:33]1[s:32][c:31]([C:29]([O:28][CH2:26][CH3:27])=[O:30])[c:35](-[c:36]2[cH:37][cH:38][c:39](-[c:42]3[c:43]([S:48][CH3:49])[cH:44][cH:45][cH:46][cH:47]3)[cH:40][cH:41]2)[c:34]1[C:50]#[N:51]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f82af42049d544cebaf8c6887e402d18
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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