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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 825402Generated: October 29, 2026

Chloride → ethyl (2RS,3RS)-2-[3-(1,1-difluoroethyl)benzyl]-3-(4-fluorophenyl)-3-hydroxypropionate

https://huagongshe.com/reaction/825402

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantSodium ionHCID 923—
ReactantBorohydrideHCID 28123—
ReactantZinc(2+)HCID 32051—
ReactantEthyl 2-[3-(1,1-difluoroethyl)benzyl]-3-(4-fluorophenyl)-3-oxopropionateHCID 22261820—
Productethyl (2RS,3RS)-2-[3-(1,1-difluoroethyl)benzyl]-3-(4-fluorophenyl)-3-hydroxypropionateHCID 86593306—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4419164567664c0391ef832704ead5bd
Source noteTest data from https://doi.org/10.1039/C8SC04228D