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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 825521Generated: October 29, 2026

Hydrochloric Acid → (-)-1-[(4-Chlorophenyl)(4-formylphenyl)methyl]-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]azetidine

https://huagongshe.com/reaction/825521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
Reactant(+)-1-{(4-Chlorophenyl)[4-(1,3-dioxolan-2-yl)phenyl]methyl}-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]-azetidineHCID 22506743—
Reactant(-)-1-[(4-Chlorophenyl)(4-formylphenyl)methyl]-3-[(3,5-difluorophenyl)methylsulfonylmethylene]azetidineHCID 86584737—
Product(-)-1-[(4-Chlorophenyl)(4-formylphenyl)methyl]-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]azetidineHCID 22506638—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8f86ccc732d947c9ad18d7c33e8c5f02
Source noteTest data from https://doi.org/10.1039/C8SC04228D