2-(Isoquinolin-8-YL)acetic acid → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-8-yl)acetamide

HRID 825727Notes

Reaction equation

HRID 825727 reaction equation
[Br:15][c:16]1[c:17](-[c:22]2[n:23][cH:24][n:25][nH:26]2)[c:18]([NH2:21])[s:19][cH:20]1.[cH:1]1[n:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([CH2:11][C:12](=[O:13])[OH:14])[c:10]12>>[cH:1]1[n:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([CH2:11][C:12](=[O:14])[NH:21][c:18]3[c:17](-[c:22]4[n:23][cH:24][n:25][nH:26]4)[c:16]([Br:15])[cH:20][s:19]3)[c:10]12

Participants

3

Reactant 2

HCID 179072422-(Isoquinolin-8-YL)acetic acidHCID 596366864-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine

Product 1

HCID 68786765N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-8-yl)acetamide

Sources & evidence

ORD record
ord-92f64467951b4e70afdd2ee7d4ed0447
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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