反应详情

温度

40 °C

To a solution of pyridine-2,3-diamine (5 g) in EtOH (150 ml) was added carbon disulfide (23 mL) at room temperature. The mixture was stirred at 40° C. under Ar for 10 h. The mixture was cooled to room temperature. The resulting white solid was filtered and washed with ether to give 1H-imidazo[4,5-b]pyridine-2-thiol (5.61 g).

1. temperatureThe mixture was cooled to room temperature
2. filtrationThe resulting white solid was filtered
3. washwashed with ether