反应详情

A mixture of N-benzyl-N-methyl-3-nitropyridin-2-amine (15 g) and 10% Pd—C (6.56 g) in EtOH (300 mL) was hydrogenated under balloon pressure at room temperature over weekend. The catalyst was removed by filtration and the filtrate was concentrated in vacuo to give N2-methylpyridine-2,3-diamine (7.00 g) as a tan solid.

1. waitwas hydrogenated under balloon pressure at room temperature over weekend
2. customThe catalyst was removed by filtration
3. concentrationthe filtrate was concentrated in vacuo