Methanol → 3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyaniline

HRID 825876Notes

Reaction equation

HRID 825876 reaction equation
[Br:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27].[CH3:1][O:2][c:3]1[c:4](-[c:13]2[c:14]([Br:19])[cH:15][n:16][n:17]2[CH3:18])[cH:5][c:6]([NH:9][C:10](=[O:11])[CH3:12])[cH:7][cH:8]1.[CH3:28][O:29][c:30]1[cH:31][cH:32][c:33]([NH:34][C:35](=[O:36])[CH3:37])[cH:38][c:39]1-[c:40]1[n:41]([CH3:42])[n:43][cH:44][cH:45]1.[CH3:48][OH:49].[Na+:47].[OH-:46]>>[CH3:1][O:2][c:3]1[c:4](-[c:13]2[c:14]([Br:19])[cH:15][n:16][n:17]2[CH3:18])[cH:5][c:6]([NH2:9])[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 67184N-bromobutanimideHCID 59514682N-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-acetamideHCID 59514683(N-[4-methoxy-3-(2-methyl-2H-pyrazol-3-yl)phenyl])acetamide

Product 1

HCID 115727413-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyaniline

Sources & evidence

ORD record
ord-49120f11d2524ba8b08bbf7b9989a218
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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