Acetone → Ethyl 2-[[7-[(2-methylpropan-2-yl)oxycarbonylamino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]acetate

HRID 825968Notes

Reaction equation

HRID 825968 reaction equation
[Br:26][CH2:27][C:28](=[O:29])[O:30][CH2:31][CH3:32].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][c:11]2[cH:12][c:13]([OH:19])[cH:14][cH:15][c:16]2[CH2:17][CH2:18]1.[C:20](=[O:21])([O-:22])[O-:23].[CH3:33][C:34](=[O:35])[CH3:36].[K+:24].[K+:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][c:11]2[cH:12][c:13]([O:19][CH2:27][C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:14][cH:15][c:16]2[CH2:17][CH2:18]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 7748Ethyl bromoacetateHCID 19660Carbonate IonHCID 22182058Tert-butyl (7-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)carbamate

Product 1

HCID 19770481Ethyl 2-[[7-[(2-methylpropan-2-yl)oxycarbonylamino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]acetate

Sources & evidence

ORD record
ord-0641a875e8c64f17b6d705560becb369
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…