(4-Methanesulfonamidophenyl)boronic acid → N-(1-Hydroxymethyl-3-methyl-butyl)-5-(4-methanesulfonylamino-phenyl)-6-(pyridin-2-ylmethoxy)-2-trifluoromethyl-nicotinamide
Reaction equation
[Br:1][c:2]1[c:3]([O:22][CH2:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[n:4][c:5]([C:18]([F:19])([F:20])[F:21])[c:6]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][CH:12]([CH3:13])[CH3:14])[CH2:15][OH:16])[cH:17]1.[CH3:30][S:31](=[O:32])(=[O:33])[NH:34][c:35]1[cH:36][cH:37][c:38]([B:41]([OH:42])[OH:43])[cH:39][cH:40]1>>[c:2]1(-[c:38]2[cH:37][cH:36][c:35]([NH:34][S:31]([CH3:30])(=[O:32])=[O:33])[cH:40][cH:39]2)[c:3]([O:22][CH2:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[n:4][c:5]([C:18]([F:19])([F:20])[F:21])[c:6]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][CH:12]([CH3:13])[CH3:14])[CH2:15][OH:16])[cH:17]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-9d9c38a269134f30a4827833f3ce86d4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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