Methanol → 3-(2-Chloroethyl)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)azetidin-2-one
Reaction equation
[CH2:30]1[CH2:31][CH:32]=[CH:33][CH2:34][CH2:35]1.[CH3:36][OH:37].[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:29])[CH:10]([CH2:26][CH2:27][Cl:28])[CH:11]2[c:12]2[cH:13][cH:14][c:15]([O:18][CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[cH:16][cH:17]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:29])[CH:10]([CH2:26][CH2:27][Cl:28])[CH:11]2[c:12]2[cH:13][cH:14][c:15]([OH:18])[cH:16][cH:17]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-81fef14ce9a045a6b769dd84951ff383
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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