Benzyl (2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate → {4-[5-Amino-2-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-2-chloro-phenyl}-carbamic acid benzyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH2:14])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[c:15]1([CH2:21][O:22][C:23]([NH:24][c:25]2[c:26]([Cl:40])[cH:27][c:28]([B:31]3[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]3)[cH:29][cH:30]2)=[O:41])[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[c:2]1(-[c:28]2[cH:27][c:26]([Cl:40])[c:25]([NH:24][C:23]([O:22][CH2:21][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)=[O:41])[cH:30][cH:29]2)[cH:3][c:4]([NH2:14])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]Participants
3
Sources & evidence
- ORD record
- ord-48ca5fca9f494a3ea9a97c331c6ed7c0
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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