Pyridine → alpha-Trifluoromethyl-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutanoate

HRID 826116Notes

Reaction equation

HRID 826116 reaction equation
[CH3:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[Cl:11])[CH:12]([CH3:13])[CH3:14])[cH:6][cH:7]1.[F:15][C:16]([CH:17]([c:18]1[cH:19][c:20]([O:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[cH:21][cH:22][cH:23]1)[OH:31])([F:32])[F:33].[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([C:9](=[O:10])[O:31][CH:17]([C:16]([F:15])([F:32])[F:33])[c:18]2[cH:19][c:20]([O:24][c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[cH:21][cH:22][cH:23]2)[CH:12]([CH3:13])[CH3:14])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 1140TolueneHCID 41780012-(4-Chlorophenyl)-3-methylbutanoyl chlorideHCID 142705712,2,2-Trifluoro-1-(3-phenoxyphenyl)ethan-1-ol

Product 1

HCID 53818390alpha-Trifluoromethyl-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutanoate

Sources & evidence

ORD record
ord-943f5309af084ab78d5b4528ec983bb2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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