2-(7-amino-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N-methyl-acetamide → 3-Chloro-2-[5-chloro-2-(3-methylcarbamoylmethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

HRID 826120Notes

Reaction equation

HRID 826120 reaction equation
[Cl:18][c:19]1[c:20]([NH:29][c:30]2[n:31][c:32]([Cl:37])[n:33][cH:34][c:35]2[Cl:36])[c:21]([C:22](=[O:23])[NH:24][CH3:25])[cH:26][cH:27][cH:28]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2)[c:32]1[n:31][c:30]([NH:29][c:20]2[c:19]([Cl:18])[cH:28][cH:27][cH:26][c:21]2[C:22](=[O:23])[NH:24][CH3:25])[c:35]([Cl:36])[cH:34][n:33]1

Participants

3

Reactant 2

HCID 672637452-(7-amino-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N-methyl-acetamideHCID 866338732-(2,5-dichloro-pyrimidin-4-ylamino)-3-chloro-N-methyl-benzamide

Product 1

HCID 672641853-Chloro-2-[5-chloro-2-(3-methylcarbamoylmethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide

Sources & evidence

ORD record
ord-097fc07fb91a4c14a38f56c7308546d1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…