1-(4-methoxyphenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-[3-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-methoxyphenyl)-5-methylpyrazole-4-carboxamide
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][c:12]([C:15](=[O:16])[OH:17])[c:13]2[CH3:14])[cH:7][cH:8]1.[NH2:18][c:19]1[cH:20][cH:21][c:22]([N:27]2[CH2:28][CH2:29][CH:30]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[CH2:31][CH2:32]2)[c:23]([C:24]#[N:25])[cH:26]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][c:12]([C:15](=[O:17])[NH:18][c:19]3[cH:20][cH:21][c:22]([N:27]4[CH2:28][CH2:29][CH:30]([N:33]5[CH2:34][CH2:35][O:36][CH2:37][CH2:38]5)[CH2:31][CH2:32]4)[c:23]([C:24]#[N:25])[cH:26]3)[c:13]2[CH3:14])[cH:7][cH:8]1Participants
3
Sources & evidence
- ORD record
- ord-339cd7e1df374ae1af53d79cb377f48f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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