Dichloromethane → 3-(Trifluoromethyl)pyrrolidin-3-ol

HRID 826337Notes

Reaction equation

HRID 826337 reaction equation
[Cl:18][CH2:19][Cl:20].[OH:1][C:2]1([C:14]([F:15])([F:16])[F:17])[CH2:3][N:4]([C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:5][CH2:6]1>>[OH:1][C:2]1([C:14]([F:15])([F:16])[F:17])[CH2:3][NH:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 50986427Tert-butyl 3-hydroxy-3-(trifluoromethyl)pyrrolidine-1-carboxylate

Product 1

HCID 509906243-(Trifluoromethyl)pyrrolidin-3-ol

Sources & evidence

ORD record
ord-247cbf9c83a24a4e8176eb4d6c78325b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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