Acetyl chloride → (2'-{[Acetyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:12]2[c:13]([CH2:22][NH:23][CH2:24][C:25]([F:26])([F:27])[F:28])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:8]([F:11])[cH:9][cH:10]1)=[O:29].[CH3:30][C:31]([Cl:32])=[O:33]>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:12]2[c:13]([CH2:22][N:23]([CH2:24][C:25]([F:26])([F:27])[F:28])[C:31]([CH3:30])=[O:33])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[c:8]([F:11])[cH:9][cH:10]1)=[O:29]Participants
3
Sources & evidence
- ORD record
- ord-fe431bf5773945768c3ba97cfeed33d0
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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