Dichloromethane → 7-Chloromethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester

HRID 826514Notes

Reaction equation

HRID 826514 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([O:18][CH2:19][S:20][CH3:21])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH2:27]([Cl:28])[Cl:29].[S:22]([Cl:23])(=[O:24])([Cl:25])=[O:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([O:18][CH2:19][Cl:25])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24648Sulfuryl chlorideHCID 60064131HCID 60064131, compound

Product 1

HCID 600641327-Chloromethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-50602193895f441d83a84afd06c405e9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…