Sulfuryl chloride → 5-chloro-3-(2-methoxyphenyl)-1-{[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl}-3-{2-oxo-2-[4-(1,3-thiazol-2-yl)piperazin-1-yl]ethyl}-1,3-dihydro-2H-indol-2-one
Reaction equation
[CH3:39][O:40][c:41]1[cH:42][c:43]([O:47][C:48]([F:49])([F:50])[F:51])[cH:44][cH:45][cH:46]1.[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]2([CH2:12][C:13]([N:14]1[CH2:15][CH2:16][N:17]([c:20]2[s:21][cH:22][cH:23][n:24]2)[CH2:18][CH2:19]1)=[O:25])[c:26]1[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]1.[S:34](=[O:35])(=[O:36])([Cl:37])[Cl:38]>>[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([S:34](=[O:35])(=[O:36])[c:44]1[c:43]([O:47][C:48]([F:49])([F:50])[F:51])[cH:42][c:41]([O:40][CH3:39])[cH:46][cH:45]1)[C:6](=[O:11])[C:5]2([CH2:12][C:13]([N:14]1[CH2:15][CH2:16][N:17]([c:20]2[s:21][cH:22][cH:23][n:24]2)[CH2:18][CH2:19]1)=[O:25])[c:26]1[c:27]([O:32][CH3:33])[cH:28][cH:29][cH:30][cH:31]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0ec660cd2fea4b46bb9f031e704fde1e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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