HRID826606

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID813

Potassium cation

K+

HCID23938

Palladium

2 次

HCID28179

Fluoride

F-

HCID31275

1,4-Dioxane

C4H8O2

HCID67331

Pyridazine, 3,6-dichloro-

C4H2Cl2N2

HCID95417

1,5-Diphenyl-1,4-pentadien-3-one

C17H14O

3 次

HCID2783132

2-Fluoro-4-methylphenylboronic acid

C7H8BFO2

PRODUCTS

生成物

HCID11665739

3-Chloro-6-(2-fluoro-4-methyl-phenyl)-pyridazine

C11H8ClFN2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-56206c61006b4aa3bae7779e587661dc
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[Cl:1][c:2]1[n:3][n:4][c:5]([Cl:8])[cH:6][cH:7]1.[F-:9].[F:11][c:12]1[c:13]([B:19]([OH:20])[OH:21])[cH:14][cH:15][c:16]([CH3:18])[cH:17]1.[K+:10].[O:30]=[C:31]([CH:32]=[CH:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)[CH:40]=[CH:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[O:48]=[C:49]([CH:50]=[CH:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1)[CH:58]=[CH:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1.[O:66]=[C:67]([CH:68]=[CH:69][c:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1)[CH:76]=[CH:77][c:78]1[cH:79][cH:80][cH:81][cH:82][cH:83]1.[Pd:28].[Pd:29]>>[Cl:1][c:2]1[n:3][n:4][c:5](-[c:13]2[c:12]([F:11])[cH:17][c:16]([CH3:18])[cH:15][cH:14]2)[cH:6][cH:7]1