Toluene → N-(3,4-Difluorobenzyl)-4,4-dimethyl-3-oxopentanamide

HRID 826699Notes

Reaction equation

HRID 826699 reaction equation
[CH2:1]([O:2][C:4]([CH2:5][C:6]([C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11])=[O:12])[CH3:3].[CH3:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[F:13][c:14]1[cH:15][c:16]([CH2:17][NH2:18])[cH:19][cH:20][c:21]1[F:22]>>[C:4]([CH2:5][C:6]([C:7]([CH3:8])([CH3:9])[CH3:10])=[O:11])(=[O:12])[NH:18][CH2:17][c:16]1[cH:15][c:14]([F:13])[c:21]([F:22])[cH:20][cH:19]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 86950Ethyl pivaloylacetateHCID 1235723,4-Difluorobenzylamine

Product 1

HCID 59762316N-(3,4-Difluorobenzyl)-4,4-dimethyl-3-oxopentanamide

Sources & evidence

ORD record
ord-9a916b11973f403ba8d031ad0211c0a1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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