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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 826907Generated: October 25, 2026

Diethyl Ether → Methyl 2-(2-(3-bromo-4-fluorophenyl)acetyl)nicotinate

https://huagongshe.com/reaction/826907

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantHydrogen iodideHCID 24841—
Reactant2,3-Dimethyl 2,3-pyridinedicarboxylateHCID 69058—
ReactantMagnesiumHCID 5462224—
Reactant3-Bromo-4-fluorobenzyl BromideHCID 12922710—
ProductMethyl 2-(2-(3-bromo-4-fluorophenyl)acetyl)nicotinateHCID 69043835—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-18f8c5800e7245a498cb3f0f9a76f1b1
Source noteTest data from https://doi.org/10.1039/C8SC04228D